重组大鼠PDGF-AA

产品货号：

GS4864

中文名称：

重组大鼠PDGF-AA

英文名称：

Recombinant Rat Platelet-derived Growth Factor-AA

产品规格：

2μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 25.3kDa,a disulfide-linked homodimeric protein containing two 111 amino acid residues polypeptide(A chain).
储存条件：冷冻（-20℃）

概述

Platelet-derived growth factor(PDGF)presenting in serum but absent from plasma was first discovered in animal study by Lynch and co-workers in the late 1980s.It is a disulfide-linked dimer consisting of two peptides-chain A and chain B.PDGF has three subforms:PDGF-AA,PDGF-BB,PDGF-AB.It is involved in a number of biological processes,including hyperplasia,embryonic neuron development,chemotaxis,and respiratory tubule epithelial cell development.The function of PDGF is mediated by two receptors(PDGFR-α and PDGFR-β).

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 5.0ng/ml,corresponding to a specific activity of>2.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4,with 5%Trehalose.
内毒素	Less than 0.1 EU/μg of rRtPDGF-AA as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in 4mMHCl to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	MSIEEAIPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATSNLN PDHREEETDV R

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